Ranmuthu CDS, Ranmuthu CKI, Khan WS. Evaluating the Current Literature on Treatments Containing Adipose-Derived Stem Cells for Osteoarthritis: a Progress Update. Current Rheumatology Reports. 2018 Sep 10;20(11):67 Review
Whitty C, Wardale J and Henson FMD (2018) The regulation of sclerostin by caphepsin K in periodontal ligament cells. Biochemical and Biophysical Research Communications, 2018 Sep 5;503(2):550-555
Woods S, Barter MJ, Elliott HR, McGillivray CM, Birch MA, Clark IM, Young DA. miR-324-5p is up regulated in end-stage osteoarthritis and regulates Indian Hedgehog signalling by differing mechanisms in human and mouse. Matrix Biology. 2018 Sep 5. [Epub ahead of print]
Steinberg J, Brooks RA, Southam L, Bhatnagar S, Roumeliotis TI, Hatzikotoulas K, Zengini E, Wilkinson JM, Choudhary JS, McCaskie AW and Zeggini E (2018) Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis. Rheumatology (Oxford). 2018 Aug 1;57(8):1481-1489
Arshad Z, Pettitt DA, Chadha P, Davies B, Carr A, Walmsley P. Artificial Intelligence to Predict Periprosthetic Joint Infection after Total Hip Replacement. International Journal of Surgery. 2018 July; 55:S8
Johnson-Lynn SE, McCaskie AW, Coll AP and Robinson AHN. Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. Bone & Joint Research. 2018 Jun 5;7(5):373-378
Turmezei TD, Treece GM, Gee AH, Houlden R, Poole KES. A new quantitative 3D approach to imaging of structural joint disease. Scientific Reports. 2018 Jun 18;8(1):9280
Yang Y, Terentjev EM, Wei Y, Ji Y. Solvent-assisted programming of flat polymer sheets into reconfigurable and self-healing 3D structures. Nat Commun. 2018 May 15;9(1):1906. Erratum in: Nat Commun. 2018 Jun 7;9(1):2291.
Ardakani AHG, Khan WS. The influence of ageing and gender in musculoskeletal stem cell. Current Stem Cell Research & Therapy, 2018 13(6), 432-437
Hulme CH, Wilson EL, Fuller HR, Roberts S, Richardson JB, Gallacher P, Peffers MJ, Shirran SL, Botting CH, Wright KT. Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation. Arthritis Research & Therapy. May 2018 2;20(1):87.
Baird A, Lindsay T, Everett A, Iyemere V, Paterson YZ, McClellan A, Henson FMD and Guest DJ. Osteoblast differentiation of equine induced pluripotent stem cells. Biology Open: 2018 May 10, 7(5)
Khan H, Mafi P, Mafi R, Khan W. The effects of ageing on differentiation and characterisation of human mesenchymal stem cells. Current stem cell research & therapy 13 (5), 378-383
MacKay JW, Kapoor G, Driban JB, Lo GH, McAlindon TE, Toms AP, McCaskie AW and Gilbert FJ. Association of subchondral bone texture on magnetic resonance imaging with radiographic knee osteoarthritis progression: data from the Osteoarthritis Initiative Bone Ancillary Study. European Radiology. 2018 May 2. [Epub ahead of print]
Sykes JG, Kuiper JH, Richardson JB, Roberts S, Wright KT, Kuiper NJ. Impact of human platelet lysate on the expansion and chondrogenic capacity of cultured human chondrocytes for cartilage cell therapy. European Cells & Materials. 2018 May 1;35:255-267.
Hodgson B, Mafi R, Mafi P, Khan WS. The Regulation of Differentiation of Mesenchymal Stem-cells into Skeletal Muscle: A Look at Signalling Molecules Involved in Myogenesis. Current stem cell research & therapy 2018 13 (5), 384-407
Gee AH, Treece GM, Poole KE. How Does the Femoral Cortex Depend on Bone Shape? A Methodology for the Joint Analysis of Surface Texture and Shape. Medical Image Analysis. 2018 Apr 45:55-67
Zengini E, Hatzikotoulas K, Tachmazidou I, Steinberg J, Hartwig FP, Southam L, Hackinger S, Boer CG, Styrkarsdottir U, Gilly A, Suveges D, Killian B, Ingvarsson T, Jonsson H, Babis GC, McCaskie A, Uitterlinden AG, van Meurs JBJ, Thorsteinsdottir U, Stefansson K, Davey Smith G, Wilkinson JM, Zeggini E. Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. Nature Genetics. 2018 Apr;50(4):549-558.
de Bari C and Roelofs AJ. Stem cell-based therapeutic strategies for cartilage defects and osteoarthritis. Current Opinion in Pharmacology. 2018 Jun;40:74-80. Epub 2018 Apr 3. Review.
Mcilroy GD, Suchacki K, Roelofs AJ, Yang W, Fu Y, Bai B, Wallace RJ, de Bari C., Cawthorn WP, Han W, Delibegović M. and Rochford JJ. Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease. Molecular Metabolism. 2018 Apr;10:55-65.
Garcia JK, Mennan C, Roberts S, Richardson J, Gallagher P, Wright K. Characterisation of synovial fluid cells of early osteoarthritis patients. Osteoarthritis and Cartilage, 2018 Apr Vol. 26, S128–S129
Mennan C, Roberts S, Garcia JK, Hulme C, Wright K . Assessing the characteristics of human mesenchymal stromal cells derived from bone marrow and umbilical cord following expansion in the quantum® hollow-fibre bioreactor system. Osteoarthritis and Cartilage, 2018 Apr Vol. 26, S146–S147
Mennan C, Garcia J, McCarthy H, Owen S, Perry J, Wright K, Banerjee R, Richardson JB, Roberts S. Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential. Cartilage, 2018 Apr 1. [Epub ahead of print]
Khan WS Outcomes of alveolar soft part sarcoma from a regional tumour unit. Acta Orthopaedica Belgica 2018 April [published online]
Khan S, Mafi P, Mafi R, Khan W. A Systematic Review of Mesenchymal Stem Cells in Spinal Cord Injury, Intervertebral Disc Repair and Spinal Fusion. Current stem cell research & therapy 2018 13 (4), 316-323
Killington K, Mafi R, Mafi P, Khan WS. A systematic review of clinical studies investigating mesenchymal stem cells for fracture non-union and bone defects. Current stem cell research & therapy 2018 13 (4), 284-291
Sano H, Kondo N, Shimakura T, Fujisawa J, Kijima Y, Kanai T, Poole KES, Yamamoto N, Takahashi HE, Endo N. Evidence for ongoing modeling-based bone formation in human femoral head trabeculae via forming minimodeling structures. A study in patients with fractures and arthritis. Frontiers in Endocrinology. 2018 Mar 19;9:88
Borakati A, Mafi R, Mafi P, Khan WS. A systematic review and meta-analysis of clinical trials of mesenchymal stem cell therapy for cartilage repair. Current stem cell research & therapy 2018 13 (3), 215-225
MacKay JW, Low SBL, Smith TO, Toms AP, McCaskie AW. and Gilbert FJ. Systematic review and meta-analysis of the reliability and discriminative validity of cartilage compositional MRI in knee osteoarthritis. Osteoarthritis and Cartilage. 2018 Mar 14. [Epub ahead of print]
Lydon H, Brooks R, McCaskie A, Henson F. Peripheral mononuclear blood cell apheresis in a preclinical ovine model. Veterinary Research. 2018 Feb 13;14(1):47.
Brown SJ, Turner, SA, Balain BS, Davidson NT, Roberts S. Is Osteogenic Differentiation of Human Nucleus Pulposus Cells a Possibility for Biological Spinal Fusion? Cartilage. 2018 Jan 1. [Epub ahead of print]
Wang L, Keatch R, Zhao Q, Wright JA, Bryant CE, Redmann AL, Terentjev EM. Influence of type-I fimbriae and fluid shear stress on bacterial behavior and multicellular architecture of early Escherichia coli biofilms at single-cell resolution. Appl Environ Microbiol. 2018 Jan 12. pii: AEM.02343-17 [Epub ahead of print]
Briggs W, Guevel B, McCaskie AW and McDonnell SM. Multi- and univariate analyses of the weekend effect for elective lower-limb joint replacements. Annals of the Royal College of Surgeons of England. 2018 Jan;100(1):42-46.
Tcacencu I, Rodrigues N, Alharbi N, Benning M, Toumpaniari S, Mancuso E, Marshall M, Bretcanu O, Birch MA, McCaskie AW and Dalgarno KW. Osseointegration of porous apatite-wollastonite and poly (lactic acid) composite structures created using 3D printing techniques. Materials Science and Engineering: C. 2018 90, 1-7
Duan P, Toumpaniari R, Partridge S, Birch MA, Genever PA, Bull SJ, Dalgarno KW, McCaskie AW and Chen J. How cell culture conditions affect the microstructure and nanomechanical properties of extracellular matrix formed by immortalized human mesenchymal stem cells: An experimental and modelling study. Materials Science and Engineering: C. 2018 89, 149-159
Reis M, McDonald D, Nicholson L, Godthardt K, Knobel S, Dickinson AM, Filby A and Wang X-N. Global phenotypic characterisation of human platelet lysate expanded MSCs by high-throughput flow cytometry. Scientific Reports 2018, 8(1), 3907.
Galarza Torre A, Shaw JE, Wood A, Gilbert HTJ, Dobre O, Genever P, Brennan K, Richardson, S.M. and Swift, J. An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness. Scientific Reports 2018 12;8(1):8981.
Etxabide A, Ribeiro RDC, Guerrero P, Ferreira AM, Stafford GP, Dalgarno KW, de la Caba K and Gentile P. Lactose-crosslinked fish gelatin-based porous scaffolds embedded with tetrahydrocurcumin for cartilage regeneration. International Journal of Biological Macromolecules, 2018 117, 199-208.
Books and Chapters
Henson FMD (2018) Equine Neck and Back Pathology 2nd Edition. Wiley, UK.
Williams N, O’Connell PR and McCaskie AW (Editors) (2018). Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
McCaskie AW and Bradley A (2018) Tissue Engineering and Regeneration Part 1: Basic Principles, ch.4, pp.33-41. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
McDonnell SM and Pandit HG (2018) History taking and clinical examination in musculoskeletal disease. Part 5: Elective Orthopaedics, ch.31 pp.436-462. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
Khanduja V and Khan W(2018) Hip and Knee Part 5: Elective Orthopaedics, ch.35 pp.511-523. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
Seah MKT, Khan W (2018) Minimally Invasive Surgery of the Hip Joint. In Iyer, K. (Ed.) (2018) Hip Joint in Adults. New York: Pan Stanford. ch.5 pp.73-85
Seah MKT, Khan W (2018) Computer-Assisted Navigation of the Hip Joint. In Iyer, K. (Ed.) (2018) Hip Joint in Adults. New York: Pan Stanford. ch.6 pp.87-99