Postdoctoral Fellow, Wellcome Trust Sanger Institute
Email: kh7@sanger.ac.uk
I am based at the Wellcome Trust Sanger Institute, where currently I am a postdoctoral fellow in the Analytical Genomics of Complex Traits group lead by Prof Eleftheria Zeggini. My principal role at the Sanger is to carry out large scale association studies of complex diseases/traits. My research interests are on underlying the genetic etiology of common diseases with a particular focus on musculoskeletal phenotypes and isolated populations.
Key publications
Gurdasani D, Carstensen T, Tekola-Ayele F, Pagani L, Tachmazidou I, Hatzikotoulas K, Karthikeyan S, Iles L, Pollard MO, Choudhury A, Ritchie GR, Xue Y, Asimit J, Nsubuga RN, Young EH, Pomilla C, Kivinen K, Rockett K, Kamali A, Doumatey AP, Asiki G, Seeley J, Sisay-Joof F, Jallow M, Tollman S, Mekonnen E, Ekong R, Oljira T, Bradman N, Bojang K, Ramsay M, Adeyemo A, Bekele E, Motala A, Norris SA, Pirie F, Kaleebu P, Kwiatkowski D, Tyler-Smith C, Rotimi C, Zeggini E, Sandhu MS (2015) The African Genome Variation Project shapes medical genetics in Africa. Nature. Jan 15;517(7534):327-32.
Panoutsopoulou K, Hatzikotoulas K, Xifara DK, Colonna V, Farmaki AE, Ritchie GR, Southam L, Gilly A, Tachmazidou I, Fatumo S, Matchan A, Rayner NW, Ntalla I, Mezzavilla M, Chen Y, Kiagiadaki C, Zengini E, Mamakou V, Athanasiadis A, Giannakopoulou M, Kariakli VE, Nsubuga RN, Karabarinde A, Sandhu M, McVean G, Tyler-Smith C, Tsafantakis E, Karaleftheri M, Xue Y, Dedoussis G, Zeggini E (2014) Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants. Nat Commun. Nov 6;5:5345
Hatzikotoulas K, Gilly A, Zeggini E (2014) Using population isolates in genetic association studies.
Brief Funct Genomics. 2014 Sep;13(5):371-7.
Tachmazidou I, Dedoussis G, Southam L, Farmaki AE, Ritchie GR, Xifara DK, Matchan A, Hatzikotoulas K, Rayner NW, Chen Y, Pollin TI, O’Connell JR, Yerges-Armstrong LM, Kiagiadaki C, Panoutsopoulou K, Schwartzentruber J, Moutsianas L; UK10K consortium, Tsafantakis E, Tyler-Smith C, McVean G, Xue Y, Zeggini E (2013) A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates. Nat Commun. 4:2872.
Hatzikotoulas K, Patikas D, Ratel S, Bassa E, Kotzamanidis C.(2014) Central and peripheral fatigability in boys and men during maximal contraction.Med Sci Sports Exerc. Jul;46(7):1326-33.
Areas of expertise
genetic association studies, statistical genetics