2017
Bell S, Terentjev EM (2017) Focal Adhesion Kinase: The reversible molecular mechanosensor. Biophys J. 112, 2439-2450
Piombo V (2017) Small animal models to understand pathogenesis of osteoarthritis and use of stem cell in cartilage regeneration. Cell Biochem Funct 35:3–11
Nakano N, Lisenda L, Khanduja V (2017) Pseudoaneurysm of a branch of the femoral circumflex artery as a complication of revision arthroscopic release of the iliopsoas tendon. SICOT J 3:26
Mancuso E, Alharbi N, Bretcanu O, et al (2017) Three-dimensional printing of porous load-bearing bioceramic scaffolds. Proc Inst Mech Eng H 231:575–585
Kazi H, Tudor F, Khan W (2017) Continued medical education (CME) focused on trauma: An opportunity for everyone not to be missed. Injury 48:205
Khan W, Bhamra J, Williams R, Morgan-Jones R (2017) “Meniscal” scar as a landmark for the joint line in revision total knee replacement. World J Orthop 8:57–61
Varley M, Markaki A, Brooks R (2017) Effect of rotation on scaffold motion and cell growth in rotating bioreactors. Tissue Eng Part A 23:522–534
Khanduja V, Lawrence JE, Audenaert E (2017) Testing the construct validity of a virtual reality hip arthroscopy smulator. Arthroscopy: The Journal of Arthroscopic & Related Surgery 33:566–571
Shaunak S, Dhinsa BS, Khan WS (2017) The role of 3D modelling and printing in orthopaedic tssue engineering: A review of the current literature. Curr Stem Cell Res Ther 12:225–232
Szostakowski B, Smitham P, Khan W (2017) Plaster of Paris-short history of casting and injured limb immobilzation. Open Orthop J 11:291–296
Steinberg J, Brooks R, McCaskie A, et al (2017) Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis. Scientific Reports
Whitmarsh T, Treece G, Gee A, Poole K (2017) An exploratory study into measuring the cortical bone thickness from CT in the presence of metal implants. Int J Comput Assist Radiol Surg
Tsegai Z, Skinner M, Gee A, et al (2017) Trabecular and cortical bone structure of the talus and distal tibia in Pan and Homo. Am J Phys Anthropol 163:784–805
Treece G (2017) Refinement of clinical X-ray computed tomography (CT) scans containing metal implants. Comput Med Imaging Graph 56:11–23
Naik A, Shepherd D, Shepherd J, et al (2017) The effect of the type of HA on the degradation of PLGA/HA composites. Mater Sci Eng C Mater Biol Appl 70:824–831
Mancuso E, Bretcanu O, Marshall M, et al (2017) Novel bioglasses for bone tissue repair and regeneration: Effect of glass design on sintering ability, ion release and biocompatibility. Materials and Design 129:239–248
Bax D, Davidenko N, Gullberg D, et al (2017) Fundamental insight into the effect of carbodiimide crosslinking on cellular recognition of collagen-based scaffolds. Acta Biomater 49:218–234
Campbell J, Husmann A, Hume R, et al (2017) Development of three-dimensional collagen scaffolds with controlled architecture for cell migration studies using breast cancer cell lines. Biomaterials 114:34–43
Lydon H, Getgood A, Henson F (2017) Healing of osteochondral defects via endochondral ossification in an ovine model. Cartilage 1947603517713818
Pillai D, Dhinsa B, Khan W (2017) Tissue engineering in achilles tendon reconstruction; the role of stem cells, growth factors and scaffolds. Curr Stem Cell Res Ther
Mayne E, Memarzadeh A, Raut P, et al (2017) Measuring hip muscle strength in patients with femoroacetabular impingement and other hip pathologies. Bone and Joint Research 6:66–72
Garner M, Alsheemeri Z, Sardesai A, Khanduja V (2017) A prospective randomized controlled trial comparing the efficacy of fascia iliaca compartment block versus local anesthetic infiltration after hip arthroscopic surgery. Arthroscopy: The Journal of Arthroscopic & Related Surgery 33:125–132
Compston J, Cooper A, Cooper C, et al (2017) UK clinical guideline for the prevention and treatment of osteoporosis. Arch Osteoporos 12:43
Khwaja M, Khan W, Ray P, Park D (2017) A retrospective study comparing crossed and lateral wire configurations in paediatric supracondylar fractures. The Open Orthopaedics Journal 11:432–438
Lawton J, Habib M, Ma B, et al (2017) The effect of cationically-modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo. J Mater Sci Mater Med 28:144
Pengas I, Nash W, Khan W, et al (2017) Coronal knee alignment 40 years after total meniscectomy in adolescents: a prospective cohort study. The Open Orthopaedics Journal 11:424–431
Williams RL, Ayre WN, Khan WS, et al (2017) Acetic acid as part of a debridement protocol during revision total knee arthroplasty. The Journal of Arthroplasty 32:953–957
Steinberg J, Ritchie G, Roumeliotis T, et al (2017) Molecular phenotyping of patient chondrocytes reveals genes and pathways involved in osteoarthritis. In: Osteoarthritis and Cartilage. pp S209–S210
Davies B, Smith J, Rikabi S, et al (2017) A quantitative, multi-national and multi-stakeholder assessment of barriers to the adoption of cell therapies. J Tissue Eng 8:
Chew E, Prakash R, Khan W (2017) Mesenchymal stem cells in human meniscal regeneration: A systematic review. Ann Med Surg (Lond) 24:3–7
Shaikh N, Seah M, Khan W (2017) Systematic review on the use of autologous matrix-induced chondrogenesis for the repair of articular cartilage defects in patients. World Journal of Orthopedics 8:588–588
Briggs W, Guevel B, McCaskie A, McDonnell S (2017) Multi- and univariate analyses of the weekend effect for elective lower-limb joint replacements. Ann R Coll Surg Engl 1–5
Davies B, Snelling S, Quek L, et al (2017) Identifying the optimum source of mesenchymal stem cells for use in knee surgery. J Orthop Res 35:1868–1875
Hackinger S, Trajanoska K, Styrkarsdottir U, et al (2017) Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus. Hum Mol Genet 26:3850–3858
Poole K, Skingle L, Gee A, et al (2017) Focal osteoporosis defects play a key role in hip fracture. Bone 94:124–134
Alizadeh M, Knapik G, Dufour J, et al (2017) An EMG-driven biomechanical model of the canine cervical spine. J Electromyogr Kinesiol 32:101–109
Khozoee B, Mafi P, Mafi R, Khan WS (2017) Mechanical stimulation protocols of human derived cells in articular cartilage tssue engineering – A systematic review. Curr Stem Cell Res Ther 12:260–270
Shepherd J, Bax D, Best S, Cameron R (2017) Collagen-Fibrinogen lyophilised scaffolds for soft tissue regeneration. Materials (Basel) 10:
Kharwadkar N, Mayne B, Lawrence JE, Khanduja V (2017) Bisphosphonates and atypical subtrochanteric fractures of the femur. Bone Joint Res 6:144–153
2016
Meng F, Terentjev EM (2016) Nonlinear elasticity of semiflexible filament networks. Soft Matter. 12, 6749-6756
Varley MC, Neelakantan S, Clyne TW, et al (2016) Cell structure, stiffness and permeability of freeze-dried collagen scaffolds in dry and hydrated states. Acta Biomaterialia 33:166–175
Carbognin E, Betto R, Soriano M, et al (2016) Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency. EMBO J 35:618–634
Davidenko N, Schuster C, Bax D, et al (2016) Evaluation of cell binding to collagen and gelatin: a study of the effect of 2D and 3D architecture and surface chemistry. J Mater Sci Mater Med 27:148
Kim Y-Y, Carloni J, Demarchi B, et al (2016) Tuning hardness in calcite by incorporation of amino acids. Nat Mater 15:903–910
Malcor J-D, Bax D, Hamaia S, et al (2016) The synthesis and coupling of photoreactive collagen-based peptides to restore integrin reactivity to an inert substrate, chemically-crosslinked collagen. Biomaterials 85:65–77
Rikkonen T, Treece G, Johannesdottir F, Poole K (2016) Focal cortical thinning is associated with lower thigh muscle area in hip fractures and controls. In: Osteoporosis International. pp S364–S364
Turmezei T, Gee A, Poole K, Treece G (2016) 3D modelling of the hip joint from clinical imaging data. Osteoarthritis and Cartilage 24:S293–S294
Turmezei T, Treece G, Gee A, et al (2016) Quantitative 3D analysis of bone in hip osteoarthritis using clinical computed tomography. Eur Radiol 26:2047–2054
Spear R, Symeonidou A, Brooks R, Markaki A (2016) In vitro assessment of porous magneto-active coatings for implant osseointegration. In: Hashmi S (ed) Reference module in materials science and materials engineering. Elsevier, Oxford, pp 1–8
Bennett SM, Arumugam M, Wilberforce S, et al (2016) The effect of particle size on the in vivo degradation of poly(d,l-lactide-co-glycolide)/α-tricalcium phosphate micro- and nanocomposites. Acta Biomater 45:340–348
Pengas I, Assiotis A, Khan W, Spalding T (2016) Adult native knee extensor mechanism ruptures. Injury 47:2065–70
Wheelton A, Mace J, Khan W, Anand S (2016) Biomaterials and fabrication to optimise scaffold properties for musculoskeletal tissue engineering. Curr Stem Cell Res Ther 11:578–84
Sobral J, Malheiro V, Clyne T, et al (2016) An accelerated buoyancy adhesion assay combined with 3-D morphometric analysis for assessing osteoblast adhesion on microgrooved substrata. J Mech Behav Biomed Mater 60:22–37
Gregory J, Barr R, Varela V, et al (2016) MRI and the distribution of bone marrow fat in hip osteoarthritis. Journal of Magnetic Resonance Imaging 45:42–50
Pawelec KM, Best SM, Cameron RE (2016) Collagen: a network for regenerative medicine. J Mater Chem B 4:6484–6496
Wong V, Narkevicius A, Chow W, et al (2016) Solid state NMR of isotope labelled murine fur: A powerful tool to study atomic level keratin structure and treatment effects. J Biomol NMR 66:93–98
Khanduja V, Baelde N, Dobbelaere A, et al (2016) Patient-specific assessment of dysmorphism of the femoral head-neck junction: a statistical shape model approach. Int J Med Robot 12:765–772
Sunil Kumar K, Lisenda L, Khanduja V (2016) Avoiding iatrogenic injury during portal placement in hip arthroscopy. annals 98:592–593
Mathews JA, Vindlacheruvu M, Khanduja V (2016) Is there a weekend effect in hip fracture patients presenting to a United Kingdom teaching hospital? World J Orthop 7:678–686
Hujazi I, Jones T, Johal S, et al (2016) The normal ischiofemoral distance and its variations. J Hip Preserv Surg 3:197–202
Lawrence JE, Khanduja V (2016) From Cape Town to Cambridge: Orthopaedic trauma in contrasting environments. World J Orthop 7:308–314
McDonnell S, Cashman J, Burges D (2016) The use of a freestanding a frame external fixator for significant bone and soft tissue loss upper limb trauma. Techniques in Orthopaedics 31:51–52
Justin A, Brooks R, Markaki A (2016) Multi-casting approach for vascular networks in cellularized hydrogels. J R Soc Interface 13:
Ferreira AM, Gentile P, Toumpaniari S, et al (2016) Impact of collagen/heparin multilayers for regulating bone cellular functions. ACS Appl Mater Interfaces 8:29923–29932
Kalia P, Brooks RA, Kinrade SD, et al (2016) Adsorption of amorphous silica nanoparticles onto hydroxyapatite surfaces differentially alters surfaces properties and adhesion of human osteoblast cells. PLOS ONE 11:e0144780
Tailor HD, Pengas Y, Khan WS (2016) Ageing and senescence in mesenchymal stem cells. In: Pham PV (ed) Stem Cell Processing. Springer International Publishing, pp 71–75
Mirams M, Ayodele B, Tatarczuch L, et al (2016) Identification of novel osteochondrosis–associated genes. J Orthop Res 34:404–411
Offeddu G, Ashworth J, Cameron R, Oyen M (2016) Structural determinants of hydration, mechanics and fluid flow in freeze-dried collagen scaffolds. Acta Biomater 41:193–203
Ashworth J, Mehr M, Buxton P, et al (2016) Parameterizing the transport pathways for cell Invasion in complex scaffold architectures. Tissue Eng Part C Methods 22:409–417
Mace J, Wheelton A, Khan W, Anand S (2016) The role of bioreactors in ligament and tendon tissue engineering. Curr Stem Cell Res Ther 11:35–40
McDonnell S, Turmezei T, Graves M, et al (2016) Advances in osteoarthritis imaging: What will make it into clinical practice? Journal of Trauma & Orthopaedics 4:60–63
Nakano N, Khanduja V (2016) Complications in hip arthroscopy. Muscles Ligaments Tendons J 6:402–409
Whitmarsh T, Treece G, Gee A, Poole K (2016) The effects on the femoral cortex of a 24 month treatment compared to an 18 month treatment with Teriparatide: A multi-trial retrospective analysis. PLoS One 11:e0147722
Davidenko N, Bax D, Schuster C, et al (2016) Optimisation of UV irradiation as a binding site conserving method for crosslinking collagen-based scaffolds. J Mater Sci Mater Med 27:14
Khan W (2016) Revision hip arthroplasty in the rheumatoid patient. MOJ Orthopedics & Rheumatology 6:
Guo G, von Meyenn F, Santos F, et al (2016) Naive pluripotent stem cells derived directly from isolated cells of the human inner cell mass. Stem Cell Reports 6:437–446
Duer M, Rajan R, Chow W, et al (2016) Nuclear magnetic resonance spectroscopy fingerprinting of tissues allows detailed analysis of glycation reactions. In: International Journal of Experimental Pathology. pp A7–A7
Berdichevski S, Brooks R, Markaki A (2016) Guiding Vascular Network Formation by Scaffold Inner Architecture. In: Tissue Engineering Part A. pp S51–S52
Hopper N, Henson F, Brooks R, et al (2016) Peripheral blood derived mononuclear cells increase chondrocyte migration. In: International Journal of Experimental Pathology. pp A6–A6
Khan W (2016) Ligament Tissue Engineering. In: Regenerative Strategies for the Treatment of Knee Joint Disabilities. Springer, pp 373–389
Allen M (2016) What’s New in Orthopaedic Basic Science. The Journal of Bone and Joint Surgery 98:2025–2029
2015
Amgarten B, Rajan R, Martínez-Sáez N, et al (2015) Collagen labelling with an azide-proline chemical reporter in live cells. Chem Commun 51:5250–5252
Kwon K, Shipley R, Edirisinghe M, et al (2015) Stress-relaxation and fatigue behaviour of synthetic brow-suspension materials. J Mech Behav Biomed Mater 42:116–128
Naik A, Best S, Cameron R (2015) The influence of silanisation on the mechanical and degradation behaviour of PLGA/HA composites. Mater Sci Eng C Mater Biol Appl 48:642–650
Pawelec K, Wardale R, Best S, Cameron R (2015) The effects of scaffold architecture and fibrin gel addition on tendon cell phenotype. J Mater Sci Mater Med 26:5349
Shepherd D, Shepherd J, Ghose S, et al (2015) The process of EDC-NHS Cross-linking of reconstituted collagen fibres increases collagen fibrillar order and alignment. APL Mater 3:
Markaki A, Öhman C, Porter A (2015) Biomaterial characterisation. Materials Science and Technology (United Kingdom) 31:129–130
Poole K, Treece G, Gee A, et al (2015) Denosumab rapidly increases cortical bone in key locations of the femur: a 3D bone mapping study in women with osteoporosis. J Bone Miner Res 30:46–54
Treece G, Gee A (2015) Independent measurement of femoral cortical thickness and cortical bone density using clinical CT. Medical Image Analysis 20:249–264
Pawelec KM, Best SM, Wardale RJ, Cameron RE (2015) Scaffold architecture and fibrin gels promote meniscal cell proliferation. APL Materials 3:014901
Pawelec KM, Shepherd J, Jugdaohsingh R, et al (2015) Collagen scaffolds as a tool for understanding the biological effect of silicates. Materials Letters 157:176–179
Duer M (2015) The contribution of solid-state NMR spectroscopy to understanding biomineralization: atomic and molecular structure of bone. J Magn Reson 253:98–110
Hopper N, Wardale J, Howard D, et al (2015) Peripheral blood derived mononuclear cells enhance the migration and chondrogenic differentiation of multipotent mesenchymal stromal cells. Stem Cells International 2015:e323454
Hopper N, Wardale J, Brooks R, et al (2015) Peripheral blood derived mononuclear cells enhance cartilage repair in in vivo osteochondral defect model. PLoS One 10:e0133937
Botelho CM, Brooks R, Kamitakahara M, et al (2015) Effect of protein adsorption onto the dissolution of silicon-substituted hydroxyapatite. Journal of Encapsulation and Adsorption Sciences 01:72–79
Gee A, Treece G, Tonkin C, et al (2015) Association between femur size and a focal defect of the superior femoral neck. Bone 81:60–66
Hopper N, Henson F, Brooks R, et al (2015) Peripheral blood derived mononuclear cells enhance osteoarthritic human chondrocyte migration. Arthritis Research & Therapy 17:199
Pawelec KM, Husmann A, Best SM, Cameron RE (2015) Altering crystal growth and annealing in ice-templated scaffolds. Journal of Materials Science 50:7537–7543
Ying Chow W, Bihan D, Forman CJ, et al (2015) Hydroxyproline ring pucker causes frustration of helix parameters in the collagen triple helix. Scientific Reports 5:12556
Haddad FS, McCaskie AW (2015) From needle to knife. The Bone & Joint Journal 97-B:1–2
Bagherifard S, Hickey DJ, de Luca AC, et al (2015) The influence of nanostructured features on bacterial adhesion and bone cell functions on severely shot peened 316L stainless steel. Biomaterials 73:185–197
Friederichs RJ, Brooks RA, Ueda M, Best SM (2015) In vitro osteoclast formation and resorption of silicon-substituted hydroxyapatite ceramics. J Biomed Mater Res 03(10):3312–22
Whitmarsh T, Treece G, Gee A, Poole K (2015) Mapping bone changes at the proximal femoral cortex of postmenopausal women in response to Alendronate and Teriparatide alone, combined or sequentially. J Bone Miner Res 30:1309–18
de Luca A, Zink M, Weidt A, et al (2015) Effect of microgrooved surface topography on osteoblast maturation and protein adsorption. J Biomed Mater Res A 103:2689–700
Pawelec KM, Husmann A, Wardale RJ, et al (2015) Ionic solutes impact collagen scaffold bioactivity. Journal of Materials Science: Materials in Medicine 26:91
Psatha M, Wu Z, Gammie FM, et al (2015) A longitudinal study of muscle rehabilitation in the lower leg after cast removal using magnetic resonance imaging and strength assessment. International Biomechanics 2:101–112
Johnson-Lynn SE, Roy S, McCaskie AW, Birch MA (2015) Electrochemical modification of titanium alloy influences osteoblast morphology and activity of cadherin-11 and Rho-Family GTPases. Journal of Biomaterials and Tissue Engineering 5:857–863
Offeddu G, Ashworth J, Cameron R, Oyen M (2015) Multi-scale mechanical response of freeze-dried collagen scaffolds for tissue engineering applications. J Mech Behav Biomed Mater 42:19–25
Mullen L, Best S, Ghose S, et al (2015) Bioactive IGF-1 release from collagen-GAG scaffold to enhance cartilage repair in vitro. J Mater Sci Mater Med 26:5325
Martínez A, Blanco M, Davidenko N, Cameron R (2015) Tailoring chitosan/collagen scaffolds for tissue engineering: Effect of composition and different crosslinking agents on scaffold properties. Carbohydr Polym 132:606–619
Kłosowski M, Friederichs R, Nichol R, et al (2015) Probing carbonate in bone forming minerals on the nanometre scale. Acta Biomaterialia 20:129–139
Friederichs R, Chappell H, Shepherd D, Best S (2015) Synthesis, characterization and modelling of zinc and silicate co-substituted hydroxyapatite. J R Soc Interface 12:20150190
Davidenko N, Schuster CF, Bax DV, et al (2015) Control of crosslinking for tailoring collagen-based scaffolds stability and mechanics. Acta Biomaterialia 25:131–142
Ashworth J, Mehr M, Buxton P, et al (2015) Cell Invasion in collagen scaffold architectures characterized by percolation theory. Advanced Healthcare Materials 4:1317–1321
Allison S, Poole K, Treece G, et al (2015) The influence of high-impact exercise on cortical and trabecular bone mineral content and 3D distribution across the proximal femur in older men: A randomized controlled unilateral intervention. J Bone Miner Res 30:1709–1716
Wavreille V, Fitzpatrick N, Drost W, et al (2015) Correlation between histopathologic, arthroscopic, and magnetic resonance imaging findings in dogs with medial coronoid disease. Vet Surg 44:501–510
Martin-Vaquero P, da Costa R, Allen M, et al (2015) Proteomic analysis of cerebrospinal fluid in canine cervical spondylomyelopathy. Spine (Phila Pa 1976) 40:601–612
Williams E, Poole K (2015) “Your”e pulling my leg!’ Tensile forces in bone preservation and atypical femoral fractures. In: Rheumatology. pp 131–131
Treece G, Gee A, Tonkin C, et al (2015) Predicting hip fracture type with cortical bone mapping (CBM) in the Osteoporotic fractures in men (MrOS) Study. J Bone Miner Res 30:2067–77
Howard D, Wardale J, Guehring H, Henson F (2015) Delivering rhFGF-18 via a bilayer collagen membrane to enhance microfracture treatment of chondral defects in a large animal model. J Orthop Res 33:1012–7
Mirams M, Ayodele B, Tatarczuch L, et al (2015) Identification of novel osteochondrosis-associated genes. J Orthop Res 34:404–11
Poole K, Treece G, Gee A, et al (2015) Response to: Comment on: “Denosumab rapidly increases cortical bone in key locations of the femur: A 3D bone mapping study in women with osteoporosis”. J Bone Miner Res 30:1939–40
Shepherd J, Friederichs R, Best S (2015) Synthetic hydroxyapatite for tissue engineering applications. In: Hydroxyapatite (HAp) for Biomedical Applications. Elsevier, pp 235–267
Cameron R, Malliaras G (2015) Preface to the special issue: Biomaterials and Bioelectronics. APL Materials 3:014601
Wong V, Reid D, Chow W, et al (2015) Preparation of highly and generally enriched mammalian tissues for solid state NMR. J Biomol NMR 63:119–123
Araujo J, Carvalho P, Best S (2015) Electrospinning of bioinspired polymer scaffolds. Adv Exp Med Biol 881:33–53
Ganguly P, Birch M (2015) Biomaterial scaffolds for mesenchymal stem cell based therapy aimed at tissue engineering application for osteoarthritis. Recent Patents on Nanomedicine 5:19–32
Gariboldi M, Best S (2015) Effect of ceramic scaffold architectural parameters on biological response. Front Bioeng Biotechnol 3:151
Pastides P, Khan W (2015) Stem cell therapy for cartilage defects. In: Stem cells: basics and clinical translation. pp 415–434
Gamie Z, Wright K, Birch M, et al (2015) The in vitro effect of TNF-Alpha on human bone marrow derived mesenchymal stem cells for use in bone tissue regeneration. In: British Journal of Surgery. pp 88–88
Justin A, Brooks R, Markaki A (2015) A perfusable, hierarchical, and three-dimensional vascular network in a collagen gel. In: Tissue Engineering Part A. pp S105–S105
Berdichevski A, Brooks R, Markaki A (2015) Co-culture systems for hierarchical vascular networks. In: Tissue Engineering Part A. pp S133–S133